In a significant advancement in nanotechnology and biomedical applications, Dr. Nidhal M. Sher Mohammed, Assistant Professor in the Department of Medicinal Chemistry, College of Pharmacy, University of Duhok (UOD), has led a study on the green synthesis of Co-Zn-Ni trimetallic oxide nanoparticles using Cicer arietinum (chickpea) leaf extract. Published in the Journal of Materials Science and Engineering: B, this research highlights the nanoparticles' remarkable antibiofilm activity, offering promising avenues for combating biofilm-associated infections.​

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Innovative Green Synthesis Approach

The study employs an eco-friendly synthesis method utilizing Cicer arietinum leaf extract, rich in phytochemicals, as both reducing and capping agents. This approach aligns with sustainable chemistry principles by minimizing the use of hazardous chemicals. The synthesized Co-Zn-Ni trimetallic oxide nanoparticles were thoroughly characterized using advanced techniques, confirming their desired structural and compositional properties.​researchgate.net

Antibiofilm Efficacy: Experimental and Computational Insights

The nanoparticles demonstrated significant antibiofilm activity against various pathogenic microorganisms. Both experimental assays and computational studies confirmed their potential to disrupt and prevent biofilm formation, which is crucial in addressing persistent infections and enhancing the effectiveness of antimicrobial treatments.

Implications for Biomedical Applications

The findings suggest that these green-synthesized nanoparticles could be integrated into medical devices, coatings, and treatments aimed at preventing biofilm-related infections. Their eco-friendly production and potent biological activity position them as promising candidates for further development in biomedical applications.​

About Dr. Nidhal M. Sher Mohammed

Dr. Nidhal M. Sher Mohammed has an extensive background in nanomaterials synthesis and analytical chemistry. She earned her Ph.D. in Instrumental Analysis/Analytical Chemistry from the University of Glasgow, UK, in 2012. Her research interests include developing and validating analytical methods for pharmaceutical drugs using spectroscopy and HPLC, with a strong focus on sustainable approaches in nanotechnology.​

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📍 UOD Media | March 2025
✍ Written by: DILAN MAJID ROSTAM