A Seminar entitled:
" Non-metastatic cutaneous squamous cell carcinoma treated with photodynamic therapy using intravenous mTHPC "
- Was presented by:Dr. Aamr Ayub Yousif
Waseem Jerjes ,a,b,⁎,
Aamr A. Yousif ,c,
Zaid Hamdoon ,d,e,
Colin Hopper ,a,e,
a UCL Medical School, London, UK
b North End Medical Centre, London, UK
c College of Pharmacy, University of Duhok, Iraq
d College of Dental Medicine, University of Sharjah, United Arab Emirates
e Unit of Oral and Maxillofacial Surgery, UCL Eastman Dental Institute, London, UK
“’Photodynamic therapy (PDT) is a relatively new method of treating various pathologies. In this retrospective study with prospective intent, a total of 22
patients with T1/T2 N0 cutaneous squamous cell carcinoma (SCC) were treated with intravenous mTHPC (meta-tetrahydroxyphenylchlorin) and surface illumination
PDT. Comparisons with the clinical features, rate of recurrence and overall outcome were made.
“’Clinical assessment revealed that 16 patients had lesions of <2cm in size (T1), while the rest were T2. No nodal involvement was identified in any of the
patients. None of the patients had a locally recurrent lesion. During the 3-year follow-up, 20/22 patients had complete response (CR) and this was after one round of
treatment. Two patients suffered from recurrent disease within 3 years of the follow-up, and they underwent surgical resection.
“’Our study confirms the advantage of using PDT in the management of T1N0 cutaneous squamous cell carcinoma.
High cure rates have been achieved using mTHPC as the photosensitiser with no report of any recurrence after 6 years of follow-up.
The technique is simple, can be easily applied in outpatient setting and have superior cosmetic results when compared to other conventional interventions.
“’The attendant No. = 20
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On Tuesday 1, 2, 2022, at 12:00 pm
At the building of the college of pharmacy