Seminars

SEMINAR- BASIC SCIENCES (BRANCH)- Dr. Hevidar M. Taha Rostinki - Heme Oxygenase-1 Has a Greater Effect on Melanoma Stem Cell Properties Than the Expression of Melanoma-Initiating Cell Markers
June 2, 2022, 1:18 a.m.

Seminar Announcement at the College of Agricultural Engineering Sciences - Department of Basic Sciences (Branch).

Seminar entitled:

"Heme Oxygenase-1 Has a Greater Effect on Melanoma Stem Cell Properties Than the Expression of Melanoma-Initiating Cell Markers"

Giving by:

Dr. Hevidar M. Taha Rostinki

on Sunday, May 29, 2022, 11:30 AM

 

Objectives or Summary : 

Melanoma-initiating cells (MICs) contribute to the tumorigenicity and heterogeneity of melanoma. MICs are identified by surface and functional markers and have been shown to display cancer stem cell (CSC) properties. However, the existence of MICs that follow the hierarchical CSC model has been questioned by studies showing that single unselected melanoma cells are highly tumorigenic in xenotransplantation assays. Herein, we characterize cells expressing MIC markers (CD20, CD24, CD133, Sca-1, ABCB1, ABCB5, ALDH high) in the B16-F10 murine melanoma cell line.

 

Place of the Seminar:

Building of the Basic Sciences (Branch), Seminar hall